Thursday, January 21, 2010

Chile: Salar de Atacama & Bipolar Disorder.

Santiago, Chile was the starting point of our recent cruise round Cape Horn. We had a wonderful guide who took us from Santiago city to the Valparaiso port, where we boarded our cruise liner. She was infectiously enthusiastic. She told us that apart from copper, agricultural products and wine, Chile produced something that was very important for her brother.  He suffers from Trastorno Afectivo Bipolar (Bipolar Disorder) and Chile is the world’s largest producer of lithium.


  Wikimedia Commons SalarDeatacamaFromChaxa.jpg
Some of the world’s most important deserts are around the Tropics of Cancer and Capricorn and here in Chile the desert called Salar de Atacama is no exception. 
Our guide told us that as the snow melts in the Andes the water went underground and dissolves the lithium salt to form lithium brine. It is pumped to the surface where the sun did the rest of the work in evaporating the water content. Lithium could then be extracted from the salt. According to Forbes, the solar energy keeps lithium extraction costs to an estimated $1,260 per ton of lithium carbonate. It sells that ton for up to $12,000.


NASA’s Earth Observatory
From the NASA website:

The Salar de Atacama in Chile is an enclosed basin with no drainage outlets. (Salar is Spanish for “salt flat.”) The salar is located in the southern half of the Atacama Desert; with no historical or current records of rainfall in some parts of this desert, it is considered to be one of the driest places on Earth.

The brines are pumped to the surface through a network of wells and into large, shallow evaporation ponds; three such evaporation facilities are visible in the center of the image. Color variations in the ponds are due to varying amounts of salts relative to water. The dry and windy climate enhances evaporation of the water, leaving concentrated salts behind for extraction of the lithium.


There is increased industrial use of lithium.  Major car manufacturers are switching to lithium batteries which are much lighter than conventional ones. It could mean 250 miles to the gallon for hybrid cars and even better for solar panel ones.
We are already using lithium batteries in a number of electronic equipments such as BlackBerrys, iPods, computers and digital cameras.


Amazing what a desert can yield!

Please spare some lithium for Bipolar Disorder though.



Lithium for Manic-Depressive Disorder (Bipolar Disorder):



Cade, John Frederick Joseph (1912 - 1980)
Taking lithium himself with no ill effect, John Cade then used it to treat ten patients with chronic or recurrent mania, on whom he found it to have a pronounced calming effect. Cade's remarkably successful results were detailed in his paper, 'Lithium salts in the treatment of psychotic excitement', published in the Medical Journal of Australia (1949). He subsequently found that lithium was also of some value in assisting depressives. His discovery of the efficacy of a cheap, naturally occurring and widely available element in dealing with manic-depressive disorders provided an alternative to the existing therapies of shock treatment or prolonged hospitalization.

In 1985 the American National Institute of Mental Health estimated that Cade's discovery of the efficacy of lithium in the treatment of manic depression had saved the world at least $US 17.5 billion in medical costs.

And many lives too!





Sunday, January 3, 2010

Good News For 2010: The Old Brain Can Learn!

Can an old brain learn, and then remember what it learns?

Grey Matter New York Times/Illustration from istockphoto.com


The New York Times  gave some encouraging news for the New Year.


As it happens, yes. While it’s tempting to focus on the flaws in older brains, that inducement overlooks how capable they’ve become. Over the past several years, scientists have looked deeper into how brains age and confirmed that they continue to develop through and beyond middle age.
Many long held views, including the one that 40 percent of brain cells are lost, have been overturned.


Remember the London Taxi Drivers?
Recently, researchers have found even more positive news. The brain, as it traverses middle age, gets better at recognizing the central idea, the big picture. If kept in good shape, the brain can continue to build pathways that help its owner recognize patterns and, as a consequence, see significance and even solutions much faster than a young person can.


Perhaps that is why some of us blog: The Jobbing Doctor, Dr Grumble.
The trick is finding ways to keep brain connections in good condition and to grow more of them.
The more we blog, the better?
“The brain is plastic and continues to change, not in getting bigger but allowing for greater complexity and deeper understanding,” says Kathleen Taylor, a professor at St. Mary’s College of California, who has studied ways to teach adults effectively. “As adults we may not always learn quite as fast, but we are set up for this next developmental step.”
Educators say that, for adults, one way to nudge neurons in the right direction is to challenge the very assumptions they have worked so hard to accumulate while young. With a brain already full of well-connected pathways, adult learners should “jiggle their synapses a bit” by confronting thoughts that are contrary to their own, says Dr. Taylor, who is 66.
 “There’s a place for information,” Dr. Taylor says. “We need to know stuff. But we need to move beyond that and challenge our perception of the world. If you always hang around with those you agree with and read things that agree with what you already know, you’re not going to wrestle with your established brain connections.”
Such stretching is exactly what scientists say best keeps a brain in tune: get out of the comfort zone to push and nourish your brain. Do anything from learning a foreign language to taking a different route to work.
Better get out my Spanish discs again as we get ready for South America!
“As adults we have these well-trodden paths in our synapses,” Dr. Taylor says. “We have to crack the cognitive egg and scramble it up. And if you learn something this way, when you think of it again you’ll have an overlay of complexity you didn’t have before — and help your brain keep developing as well.” New York Times  :BARBARA STRAUCH